MRI guided wire localization muscle biopsy in a child with juvenile dermatomyositis

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MRI guided wire localization muscle biopsy in a child with juvenile dermatomyositis

A novel technique for preoperative MRI guided wire localization for targeted surgical excisional biopsy of muscle is described in a pediatric patient with juvenile dermatomyositis (JDM). This technique allows for preoperative localization of abnormalities seen only with MRI. Using this technique, the patient underwent successful targeted muscle biopsy for confirmation of the diagnosis and stagi...

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Muscle pathology in juvenile dermatomyositis.

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Muscle Biopsy Findings in Combination With Myositis‐Specific Autoantibodies Aid Prediction of Outcomes in Juvenile Dermatomyositis

OBJECTIVE Juvenile dermatomyositis (DM) is a rare and severe autoimmune condition characterized by rash and proximal muscle weakness. While some patients respond to standard treatment, others do not. This study was carried out to investigate whether histopathologic findings and myositis-specific autoantibodies (MSAs) have prognostic significance in juvenile DM. METHODS Muscle biopsy samples (...

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Maternal microchimerism in muscle biopsies from children with juvenile dermatomyositis

OBJECTIVE Recent advances in molecular techniques have revealed that there is bi-directional transfer of cells between mother and child during pregnancy, and the presence of a mother's cells in her child has been termed maternal microchimerism (MMc). There is the potential for maternal cells to provoke inappropriate immune responses in the child, which could be a factor in autoimmunity includin...

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MRI guided muscle biopsy confirmed polymyositis diagnosis in a patient with interstitial lung disease.

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2013

ISSN: 1546-0096

DOI: 10.1186/1546-0096-11-15